Introduction to Diabetes Research, 2 hp

Subject course
Cardiovascular diseases, Inflammation, Metabolism,  
Olof Idevall, Meena Daivadanam
Medical Cell Biology, Woman's and Children's health
BMC, Husargatan 3
Box 571, 75123 Uppsala
11-15/9 2023
5 days

This course aims to give an introduction to important topics related to diabetes. The course curriculum includes lectures on different aspects of diabetes, including common causes of diabetes, physiological and metabolic changes associated with diabetes, strategies to prevent and treat diabetes and the societal impact of the disease. These theoretical parts are also mixed with group work where participants will discuss some of
these topics, put them in context and orally present conclusions. The course is suitable for doctoral students affiliated with Uppsala Diabetes Center (UDC) or the research tracks “Metabolism”, “Inflammation” and “Cardiovascular”, but also open to other applicants.

After completion of the course, the participants are expected to:
• Account for the diabetes situation globally and to discuss differences and
similarities in preventive methods in different contexts.
• Explain the basic biology, pathology and treatment of different types of diabetes.
• Describe and critically discuss the social, economic and environmental challenges we face regarding diabetes.

Islet physiology and regeneration
• History of diabetes and its classification and pathogenesis
• Structure and function of the pancreatic islets of Langerhans
• Islet regeneration and replacement strategies
Metabolism and complications
• Metabolic changes in type-2 diabetes
• Obesity and treatment of obesity
• Cardiovascular and renal complications in diabetes
• Current and novel treatments for type-1 and type-2 diabetes
Immunology, infections and host-microbe interactions
• The immune system and diabetes
• Gut microbiota and diabetes
• Diabetes in animals
The individual, society and diabetes
• The global diabetes situation
• The patient perspective
• Swedish National Diabetes Register (NDR) and other national health and quality
• Differences and similarities in preventive methods in different contexts
• Social, economic, environmental and societal challenges of diabetes

The course participants will also present their own research in the form of a poster.

In case the number of applications exceeds the maximum number of course participants (set to 22), priority will be given in the following order: UDC-affiliated doctoral students, other doctoral students from Uppsala University, doctoral students from other Universities.

Attendance at compulsory lectures and active participation in seminars, case- and group work are required to pass the course. Up to two missed compulsory activities can be compensated for by written reports. More extensive absence will have to be complemented by attendance at a later course.

Relevant literature in the form of original and review articles will be provided before the start of the course.

Olof Idevall, Sebastian Barg, Ulf Risérus, Jan Eriksson, Maria Eriksson Svensson, Emma Strage (SLU), Sanna Truelsen Lindåse (SLU), Joey Lau Börjesson, Gustaf Christofersson, Shafqat Ahmad, Katarina Eeg-Olofsson, Meena Daivadanam, Taeda Tomic, Beatrice Kennedy mfl.

Olof Idevall (
Meena Daivadanam (

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